Uchiha Sasuke heads for an astronomical observatory far from the Land of Fire where he joins up with Sakura and dives into an undercover investigation to search for traces of the Sage of Six Paths! There, they discover a plan that goes beyond life and death… Where will the battle take this husband-and-wife team?

In a mysterious institution, Familie, girls get raised. Kurumi, a girl who lives there, fell asleep the day before her 10th birthday. When she woke up, 14 years had passed. A mysterious journey begins to return to the places she doesn't know, her friends, and her lost memories.